FRC
FRC Logo
Sign InGet Access

Connect With Us

Stay updated with our latest research and insights

Fundamental Research Corp Logo

Highly ranked equity research firm providing institutional grade tools and analysis to all investors worldwide. Trusted by global investors for over 20+ years.

20+ Years
Rate us on TrustpilotLeave a review

Policies

  • Privacy Policy
  • Terms of Service
  • Disclaimer

Company

  • About Us
  • Our Team
  • Contact Us
  • Leave a Review

Resources

  • Videos
  • Research Reports
  • FAQ
  • How to use FRC

Browse

  • Stock Directory
  • Stock Screener
  • Market Intel Weekly
  • Report Archive

Trackers

  • Congress Trading
  • Senate Trading
  • Congress Net Worth
  • Commodities

© 2026 Fundamental Research Corp. All Rights Reserved.

Professional investment research since 2003

Home
Research
Get Access
Sign In
NuCana plc Stock AnalysisComprehensive stock analysis for NuCana plc (NCNA) including live price, Snowflake performance metrics, financial statements, and investment research.Stock AnalysisNCNA
NCNA
NuCana plc
  • Company Overview
  • FRC Research
  • Financial Data
  • Peer Comparison
  • Ownership & News
NCNA
Home🔹Stocks🔹NuCana plc

NuCana plc

🇺🇸NCNA•NASDAQ

NuCana plc

🇺🇸NCNA•NASDAQ
Market cap
$8.02M
Sentiment

Your view on NCNA

Mkt Cap
$8.02M
Sentiment
Your view
NCNA
NuCana plc
  • Company Overview
  • FRC Research
  • Financial Data
  • Peer Comparison
  • Ownership & News
NCNA
Company Overview

Overview

What the company does, where it operates, and who runs it.

About NuCana plc

Industry
Biotechnology
Sector
Healthcare
CEO
Hugh Stephen Griffith
Headquarters
3 Lochside Way, Edinburgh, GB
Industry
Biotechnology
Sector
Healthcare
CEO
Hugh Stephen Griffith
Headquarters
3 Lochside Way, Edinburgh, GB
Description

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of products for the treatment of cancer. The company develops its products based on its proprietary ProTide technology.

Its lead product candidate includes Acelarin, which is in Phase I clinical trial for patients with advanced solid tumors; Phase Ib for patients with recurrent ovarian cancer; Phase Ib clinical trials for the treatment of patients with biliary tract cancer; Phase II clinical trial for the treatment of patients with platinum-resistant ovarian cancer; and Phase III clinical trial for the treatment of patients with pancreatic cancer.

The company is also developing NUC-3373, a ProTide transformation of the active anti-cancer metabolite of 5-fluorouracil, which is in Phase I clinical trial for the treatment of patients with advanced solid tumors and in a Phase 1b/2 clinical trial for patients with advanced colorectal cancer; and NUC-7738, a nucleoside analog that is in Phase 1/2 clinical trial for the treatment of patients with advanced solid tumors and hematological tumors.

It has a research, collaboration, and license agreement with Cardiff University and University College Cardiff Consultants Ltd. for the design, synthesis, characterization, and evaluation of ProTides; and an assignment, license, and collaboration agreement with Cardiff ProTides Ltd. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017.

NuCana plc was incorporated in 1997 and is headquartered in Edinburgh, the United Kingdom.

FRC Research

Media

Infographics, videos, and posts covering the company.

Financial Data

Stock Data

Price chart, volume, and trading data.

Fair Value

What FRC thinks it is worth vs. the current price.

FRC's fair value estimate for NuCana plc, and the rating behind it. NCNA last traded at $1.32; the estimate is read against that market price. FRC analysts run the firm's valuation model across the companies on this platform to estimate what each one is worth, rather than republishing a consensus average. Shows the current estimate, our rating, and when it was last revised. A free account covers 7 company valuations a month; a paid subscription is unlimited.

Financial Ratios

Profitability, returns, valuation, and leverage ratios.

Valuation, profitability, liquidity and leverage ratios for NuCana plc. Starting points for NuCana plc: EPS -$2.32, beta 2.24 — an Biotechnology name. P/E, P/B, EV/EBITDA, margins, return on equity, current ratio and debt coverage, each shown against the company's own history.

Dividend Analysis

Yield, payout ratio, and dividend coverage metrics.

Dividend history, yield and payout sustainability for NuCana plc. NuCana plc does not currently pay a regular dividend, so this section tracks capacity rather than history. Per-share payments, yield over time, payout ratio and growth streak, with coverage measured against free cash flow.

Earnings Analysis

EPS history, beat rate, and upcoming earnings reports.

Reported vs. expected earnings history for NuCana plc. Trailing twelve-month EPS for NuCana plc stands at -$2.32. EPS surprises by quarter, revenue against estimates, and the upcoming reporting date.

Financial Statements

Income statement, balance sheet, and cash flow statements.

Income statement, balance sheet and cash flow history for NuCana plc. NuCana plc has reported as a listed company since 2017. Annual and quarterly filings with period-over-period comparison, so you can trace how revenue, margins and cash generation have moved.

Peer Comparison

Comparables

List of peer companies in the same industry.

NuCana plc valued side by side against its closest peers. NuCana plc is measured against Biotechnology peers within the Healthcare sector. Peer-relative multiples and operating metrics, so the valuation is read in the context of its own sector rather than in isolation.

Ownership & News

Institutional Ownership

Premium

Which funds and firms own the stock.

Which institutions hold NuCana plc, and how their positions are changing. At a $8.0M market value, institutional positions materially move NuCana plc's register. Top holders, position sizes, and quarter-over-quarter accumulation or distribution from regulatory filings. Included with FRC Premium.

Insider Trading

Premium

Recent buying and selling by company executives.

Buying and selling by NuCana plc executives and directors. Shares of NuCana plc have traded between $2.78 and $330.00 over the past 52 weeks — context for the timing of the transactions below. Insider transactions as disclosed to regulators, with role, size and date — the clearest read on how the people running the company are positioned. Included with FRC Premium.

Senate Trading

Premium

U.S. Senator disclosures filed under the STOCK Act.

U.S. Senate disclosures naming NuCana plc. NuCana plc is a $8.0M Healthcare company. Senators' reported transactions in this security, alongside the fundamentals — a signal most research platforms leave out entirely. Included with FRC Premium.

House Trading

Premium

U.S. Representative disclosures filed under the STOCK Act.

U.S. House of Representatives disclosures naming NuCana plc. Representatives' reported transactions in this security, shown next to the company's fundamentals. Included with FRC Premium.

News

Latest headlines and market coverage.

Latest headlines and company announcements for NuCana plc. Coverage tracks NuCana plc within Biotechnology (Healthcare). Press releases and market coverage, newest first.

Peer companies

  • CLGN — CollPlant Biotechnologies Ltd.
  • ENLV — Enlivex Therapeutics Ltd.
  • GDTC — CytoMed Therapeutics Limited
  • LSTA — Lisata Therapeutics, Inc.
  • MTVA — MetaVia Inc.
  • NRSN — NeuroSense Therapeutics Ltd.

More Biotechnology companies

  • MIRM — Mirum Pharmaceuticals, Inc.
  • MIST — Milestone Pharmaceuticals Inc.
  • MLEC — Moolec Science S.A.
  • MLECW — Moolec Science S.A.
  • MLLCF — Molecular Partners AG
  • MLTX — MoonLake Immunotherapeutics
  • MLYS — Mineralys Therapeutics, Inc.
  • MMIRF — MedMira Inc.
  • MNKD — MannKind Corporation
  • MNOV — MediciNova, Inc.
  • MNPR — Monopar Therapeutics Inc.
  • MOLN — Molecular Partners AG

News

Latest Market News