Rhythm Pharmaceuticals, Inc.
Rhythm Pharmaceuticals, Inc.
Your view on RYTM
Overview
What the company does, where it operates, and who runs it.
About Rhythm Pharmaceuticals, Inc.
- Industry
- Biotechnology
- Sector
- Healthcare
- CEO
- David P. Meeker
- Headquarters
- 222 Berkeley Street, Boston, MA, US
- Industry
- Biotechnology
- Sector
- Healthcare
- CEO
- David P. Meeker
- Headquarters
- 222 Berkeley Street, Boston, MA, US
Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the development and commercialization of therapeutics for the treatment of rare genetic diseases of obesity.
The company's lead product candidate is IMCIVREE, a potent melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, and Bardet-Biedl and Alström syndrome.
It is also developing setmelanotide, which is in Phase II clinical trials for treating POMC or LEPR heterozygous deficiency obesities, steroid receptor coactivator 1 deficiency obesity, SH2B1 deficiency obesity, MC4 receptor deficiency obesity, Smith-Magenis syndrome obesity, POMC epigenetic disorders, and other MC4R disorders.
Rhythm Pharmaceuticals, Inc. has a collaborative research agreement with the Clinical Registry Investigating Bardet-Biedl Syndrome. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015.
Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.
Stock Data
Price chart, volume, and trading data.
Fair Value
What FRC thinks it is worth vs. the current price.
Fair value for Rhythm Pharmaceuticals, Inc. from FRC's valuation model, read against the market price. RYTM last traded at $112.16; the estimate is read against that market price. The model runs on every stock on the platform and shows the estimate per share and the date it was calculated. A free account covers 3 company valuations a month; a paid subscription is unlimited.
Financial Ratios
Profitability, returns, valuation, and leverage ratios.
Valuation, profitability, liquidity and leverage ratios for Rhythm Pharmaceuticals, Inc.. Starting points for Rhythm Pharmaceuticals, Inc.: EPS -$2.81, beta 2.13 — an Biotechnology name. P/E, P/B, EV/EBITDA, margins, return on equity, current ratio and debt coverage, each shown against the company's own history.
Dividend Analysis
Yield, payout ratio, and dividend coverage metrics.
Dividend history, yield and payout sustainability for Rhythm Pharmaceuticals, Inc.. Rhythm Pharmaceuticals, Inc. does not currently pay a regular dividend, so this section tracks capacity rather than history. Per-share payments, yield over time, payout ratio and growth streak, with coverage measured against free cash flow.
Earnings Analysis
EPS history, beat rate, and upcoming earnings reports.
Reported vs. expected earnings history for Rhythm Pharmaceuticals, Inc.. Trailing twelve-month EPS for Rhythm Pharmaceuticals, Inc. stands at -$2.81. EPS surprises by quarter, revenue against estimates, and the upcoming reporting date.
Analyst Estimates
Analysts' price targets, ratings, and revenue and EPS estimates.
1-Year Price Target
Low
$120.00
Median
$154.00
High
$160.00
Average target · 1 new target in the last month, average $130.00
Analyst Ratings
- Strong Buy0
- Buy22
- Hold0
- Sell0
- Strong Sell0
Earnings Estimate
| EPS | Current QtrDec 2026 | Next QtrMar 2027 | Current YearFY Dec 2026 | Next YearFY Dec 2027 |
|---|---|---|---|---|
| Avg. estimate | -$2.59 | -$0.52 | -$4.80 | -$1.03 |
| Low estimate | -$5.81 | -$0.63 | -$8.98 | -$2.74 |
| High estimate | -$0.56 | -$0.43 | -$2.58 | $0.04 |
| No. of analysts | 10 | 3 | 12 | 11 |
| Year-ago EPS | -$0.73 | -$0.83 | -$3.11 | — |
| Growth | -255.2% | +37.6% | -54.4% | — |
Revenue Estimate
| Revenue | Current QtrDec 2026 | Next QtrMar 2027 | Current YearFY Dec 2026 | Next YearFY Dec 2027 |
|---|---|---|---|---|
| Avg. estimate | $109.65M | $113.42M | $332.01M | $572.69M |
| Low estimate | $103.37M | $113.27M | $319.51M | $521.57M |
| High estimate | $118.58M | $113.58M | $342.56M | $619.47M |
| No. of analysts | 11 | 4 | 13 | 14 |
| Year-ago revenue | $57.25M | $60.11M | $189.76M | — |
| Growth | +91.5% | +88.7% | +75.0% | — |
Source: Wall Street analysts' published price targets, ratings and estimates, compiled by Financial Modeling Prep from StreetInsider, Benzinga; as of Nov 12, 2026. Not FRC research or a recommendation.
Financial Statements
Income statement, balance sheet, and cash flow statements.
Income statement, balance sheet and cash flow history for Rhythm Pharmaceuticals, Inc.. Rhythm Pharmaceuticals, Inc. has reported as a listed company since 2017. Annual and quarterly filings with period-over-period comparison, so you can trace how revenue, margins and cash generation have moved.
Comparables
List of peer companies in the same industry.
Rhythm Pharmaceuticals, Inc. valued side by side against its closest peers. Rhythm Pharmaceuticals, Inc. is measured against Biotechnology peers within the Healthcare sector. Peer-relative multiples and operating metrics, so the valuation is read in the context of its own sector rather than in isolation.
Institutional Ownership
Which funds and firms own the stock.
Which institutions hold Rhythm Pharmaceuticals, Inc., and how their positions are changing. At a $7.78B market value, institutional positions materially move Rhythm Pharmaceuticals, Inc.'s register. Top holders, position sizes, and quarter-over-quarter accumulation or distribution from regulatory filings.
Insider Trading
Recent buying and selling by company executives.
Buying and selling by Rhythm Pharmaceuticals, Inc. executives and directors. Shares of Rhythm Pharmaceuticals, Inc. have traded between $45.91 and $116.00 over the past 52 weeks — context for the timing of the transactions below. Insider transactions as disclosed to regulators, with role, size and date — the clearest read on how the people running the company are positioned.
News
Latest headlines and market coverage.
Latest headlines and company announcements for Rhythm Pharmaceuticals, Inc.. Coverage tracks Rhythm Pharmaceuticals, Inc. within Biotechnology (Healthcare). Press releases and market coverage, newest first.
Comments
Comments and replies from FRC members about this company.
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