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Ionis Pharmaceuticals, Inc. Stock AnalysisComprehensive stock analysis for Ionis Pharmaceuticals, Inc. (IONS) including live price, Snowflake performance metrics, financial statements, and investment research.Stock AnalysisIONS
IONS
Ionis Pharmaceuticals, Inc.
  • Company Overview
  • FRC Research
  • Financial Data
  • Peer Comparison
  • Ownership & News
IONS
Home🔹Stocks🔹Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals, Inc.

🇺🇸IONS•NASDAQ

Ionis Pharmaceuticals, Inc.

🇺🇸IONS•NASDAQ
Market cap
$9.01B
Sentiment

Your view on IONS

Mkt Cap
$9.01B
Sentiment
Your view
IONS
Ionis Pharmaceuticals, Inc.
  • Company Overview
  • FRC Research
  • Financial Data
  • Peer Comparison
  • Ownership & News
IONS
Company Overview

Overview

What the company does, where it operates, and who runs it.

About Ionis Pharmaceuticals, Inc.

Industry
Biotechnology
Sector
Healthcare
CEO
Brett P. Monia
Headquarters
2855 Gazelle Court, Carlsbad, CA, US
Industry
Biotechnology
Sector
Healthcare
CEO
Brett P. Monia
Headquarters
2855 Gazelle Court, Carlsbad, CA, US
Description

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States.

The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and WAYLIVRA, a treatment for familial chylomicronemia syndrome and familial partial lipodystrophy.

It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of TTR amyloidosis; Olezarsen for patients with severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Tofersen to inhibit the production of superoxide dismutase 1.

In addition, the company develops medicines for metabolic diseases, infectious diseases, renal diseases, ophthalmic diseases, and cancer.

It has a strategic collaboration with Biogen Inc.; and collaboration and license agreement with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc. Ionis Pharmaceuticals, Inc. was founded in 1989 and is based in Carlsbad, California.

FRC Research

Media

Infographics, videos, and posts covering the company.

Financial Data

Stock Data

Price chart, volume, and trading data.

Fair Value

What FRC thinks it is worth vs. the current price.

FRC's fair value estimate for Ionis Pharmaceuticals, Inc., and the rating behind it. IONS last traded at $54.21; the estimate is read against that market price. FRC analysts run the firm's valuation model across the companies on this platform to estimate what each one is worth, rather than republishing a consensus average. Shows the current estimate, our rating, and when it was last revised. A free account covers 7 company valuations a month; a paid subscription is unlimited.

Financial Ratios

Profitability, returns, valuation, and leverage ratios.

Valuation, profitability, liquidity and leverage ratios for Ionis Pharmaceuticals, Inc.. Starting points for Ionis Pharmaceuticals, Inc.: EPS -$3.41, beta 0.42 — an Biotechnology name. P/E, P/B, EV/EBITDA, margins, return on equity, current ratio and debt coverage, each shown against the company's own history.

Dividend Analysis

Yield, payout ratio, and dividend coverage metrics.

Dividend history, yield and payout sustainability for Ionis Pharmaceuticals, Inc.. Ionis Pharmaceuticals, Inc. does not currently pay a regular dividend, so this section tracks capacity rather than history. Per-share payments, yield over time, payout ratio and growth streak, with coverage measured against free cash flow.

Earnings Analysis

EPS history, beat rate, and upcoming earnings reports.

Reported vs. expected earnings history for Ionis Pharmaceuticals, Inc.. Trailing twelve-month EPS for Ionis Pharmaceuticals, Inc. stands at -$3.41. EPS surprises by quarter, revenue against estimates, and the upcoming reporting date.

Financial Statements

Income statement, balance sheet, and cash flow statements.

Income statement, balance sheet and cash flow history for Ionis Pharmaceuticals, Inc.. Ionis Pharmaceuticals, Inc. has reported as a listed company since 1991. Annual and quarterly filings with period-over-period comparison, so you can trace how revenue, margins and cash generation have moved.

Peer Comparison

Comparables

List of peer companies in the same industry.

Ionis Pharmaceuticals, Inc. valued side by side against its closest peers. Ionis Pharmaceuticals, Inc. is measured against Biotechnology peers within the Healthcare sector. Peer-relative multiples and operating metrics, so the valuation is read in the context of its own sector rather than in isolation.

Ownership & News

Institutional Ownership

Premium

Which funds and firms own the stock.

Which institutions hold Ionis Pharmaceuticals, Inc., and how their positions are changing. At a $9.01B market value, institutional positions materially move Ionis Pharmaceuticals, Inc.'s register. Top holders, position sizes, and quarter-over-quarter accumulation or distribution from regulatory filings. Included with FRC Premium.

Insider Trading

Premium

Recent buying and selling by company executives.

Buying and selling by Ionis Pharmaceuticals, Inc. executives and directors. Shares of Ionis Pharmaceuticals, Inc. have traded between $23.95 and $76.78 over the past 52 weeks — context for the timing of the transactions below. Insider transactions as disclosed to regulators, with role, size and date — the clearest read on how the people running the company are positioned. Included with FRC Premium.

Senate Trading

Premium

U.S. Senator disclosures filed under the STOCK Act.

U.S. Senate disclosures naming Ionis Pharmaceuticals, Inc.. Ionis Pharmaceuticals, Inc. is a $9.01B Healthcare company. Senators' reported transactions in this security, alongside the fundamentals — a signal most research platforms leave out entirely. Included with FRC Premium.

House Trading

Premium

U.S. Representative disclosures filed under the STOCK Act.

U.S. House of Representatives disclosures naming Ionis Pharmaceuticals, Inc.. Representatives' reported transactions in this security, shown next to the company's fundamentals. Included with FRC Premium.

News

Latest headlines and market coverage.

Latest headlines and company announcements for Ionis Pharmaceuticals, Inc.. Coverage tracks Ionis Pharmaceuticals, Inc. within Biotechnology (Healthcare). Press releases and market coverage, newest first.

Peer companies

  • ASND — Ascendis Pharma A/S
  • BBIO — BridgeBio Pharma, Inc.
  • BMRN — BioMarin Pharmaceutical Inc.
  • EXEL — Exelixis, Inc.
  • GH — Guardant Health, Inc.
  • MDGL — Madrigal Pharmaceuticals, Inc.
  • MRNA — Moderna, Inc.
  • ROIV — Roivant Sciences Ltd.

More Biotechnology companies

  • CADL — Candel Therapeutics, Inc.
  • CAI — Caris Life Sciences, Inc.
  • CAIHF — Chia Tai Enterprises International Limited
  • CALA — Calithera Biosciences, Inc.
  • CALC — CalciMedica, Inc.
  • CAMP — CAMP4 Therapeutics Corporation
  • CAMRF — Camurus AB (publ)
  • CANF — Can-Fite BioPharma Ltd.
  • CAPR — Capricor Therapeutics, Inc.
  • CARM — Carisma Therapeutics, Inc.
  • CASBF — CanSino Biologics Inc.
  • CASIF — CASI Pharmaceuticals, Inc.

ETFs holding Ionis Pharmaceuticals, Inc.

  • MEDX — Horizon Kinetics Medical ETF (3.25%)
  • TSCM — The 2023 ETF Series Trust - TimesSquare Quality Mid Cap Growth ETF (3.24%)
  • TMFS — Motley Fool Small-Cap Growth ETF (3.16%)
  • TMFM — Motley Fool Mid-Cap Growth ETF (2.46%)
  • ARKG — ARK Genomic Revolution ETF (1.78%)
  • FFOX — FundX Investment Trust (1.73%)

News

Latest Market News